A basic limitation on inferring phylogenies by pairwise sequence comparisons
نویسندگان
چکیده
منابع مشابه
A basic limitation on inferring phylogenies by pairwise sequence comparisons.
Distance-based approaches in phylogenetics such as Neighbor-Joining are a fast and popular approach for building trees. These methods take pairs of sequences, and from them construct a value that, in expectation, is additive under a stochastic model of site substitution. Most models assume a distribution of rates across sites, often based on a gamma distribution. Provided the (shape) parameter ...
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ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2009
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2008.10.010